@import url("https://maxcdn.bootstrapcdn.com/font-awesome/4.7.0/css/font-awesome.min.css");

@import url("https://use.typekit.net/hov4jfo.css");

@import url('https://fonts.googleapis.com/css2?family=Open+Sans:ital,wght@0,300;0,400;0,700;0,800;1,300;1,400;1,700;1,800&display=swap');

@font-face {
  font-family: "HelveticaNeue";
  src: url("/content/dam/open-digital/lynparza/en/fonts/HelveticaNeue.woff") format("woff");
  font-style: normal;
  font-weight: normal;
}

@font-face {
  font-family: "HelveticaNeueLight";
  src: url("/content/dam/open-digital/lynparza/en/fonts/HelveticaNeueLight.woff") format("woff");
  font-style: normal;
  font-weight: normal;
}

@font-face {
  font-family: "HelveticaLight";
  src: url("/content/dam/open-digital/lynparza/en/fonts/HelveticaLT45Light.woff") format("woff");
  font-style: normal;
  font-weight: normal;
}

@font-face {
  font-family: 'HelveticaNeue-Medium';
  src: url("/content/dam/open-digital/lynparza/en/fonts/HelveticaNeue-Medium.woff") format("woff");
  font-style: normal;
  font-weight: normal;
}

@font-face {
  font-family: "HelveticaHeavy";
  src: url("/content/dam/open-digital/lynparza/en/fonts/HelveticaNeueHeavy.woff") format("woff");
  font-style: normal;
  font-weight: normal;
}

@font-face {
  font-family: "HelveticaNeue-Roman";
  src: url("/content/dam/open-digital/lynparza/en/fonts/HelveticaNeue-Roman.woff") format("woff");
  font-style: normal;
  font-weight: normal;
}

@font-face {
  font-family: "HelveticaNeue-Bold";
  src: url("/content/dam/open-digital/lynparza/en/fonts/HelveticaNeue-Bold.woff") format("woff");
  font-style: normal;
  font-weight: normal;
}

@font-face {
  font-family: "AlbertSans";
  src: url("/content/dam/open-digital/lynparza/en/fonts/albert-sans/AlbertSans-VariableFont_wght.ttf") format("truetype");
  font-style: normal;
  font-weight: normal;
}

@font-face {
  font-family: "AlbertSans-Italic";
  src: url("/content/dam/open-digital/lynparza/en/fonts/albert-sans/AlbertSans-Italic-VariableFont_wght.ttf") format("truetype");
  font-style: italic;
  font-weight: normal;
}
@font-face {
  font-family: "Inter-extra-light";
  src: url("/content/dam/open-digital/lynparza/en/fonts/inter/Inter_18pt-Light.ttf") format("truetype");
  font-style: normal;
  font-weight: 200;
}
@font-face {
  font-family: "Inter-light";
  src: url("/content/dam/open-digital/lynparza/en/fonts/inter/Inter_18pt-Light.ttf") format("truetype");
  font-style: normal;
  font-weight: 300;
}

@font-face {
  font-family: "Inter-regular";
  src: url("/content/dam/open-digital/lynparza/en/fonts/inter/Inter_18pt-Regular.ttf") format("truetype");
  font-style: normal;
  font-weight: 400;
}

@font-face {
  font-family: "Inter-semibold";
  src: url("/content/dam/open-digital/lynparza/en/fonts/inter/Inter_18pt-SemiBold.ttf") format("truetype");
  font-style: normal;
  font-weight: 600;
}

@font-face {
  font-family: "Inter-bold";
  src: url("/content/dam/open-digital/lynparza/en/fonts/inter/Inter_18pt-Bold.ttf") format("truetype");
  font-style: normal;
  font-weight: 700;
}

@font-face {
  font-family: "Inter-black";
  src: url("/content/dam/open-digital/lynparza/en/fonts/inter/Inter_18pt-Black.ttf") format("truetype");
  font-style: normal;
  font-weight: 900;
}

#CookieReportsOverlay,
#CookieReportsBannerAZ {
  z-index: 33002 !important;
}

p,
b,
strong,
ul li,
ol li {
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
  font-size: 17px;
  line-height: 21px;
  color: #000;
}

.sm-text p,
.sm-text ol li {
  font-size: 14px;
  line-height: 20px !important;
}

.ae-section p {
  font-size: 16px;
  line-height: 21px;
  color: #004D74;
}

.gr-bullet li {
  padding-left: 5px;
}

.hcp-strapline {
  position: absolute;
  top: 0;
  background: #e0eaee;
  height: auto;
  padding: 0;
  z-index: 1;
}

.hcp-strapline-2 {
  position: absolute;
  top: 72px;
  background: #e0eaee;
  height: 41px;
  padding: 0;
  z-index: 2;
}

.resources .hcp-strapline {
  top: 73px;
}

.hcp-strapline p {
  font-size: 16px;
  line-height: normal;
  font-weight: bold;
  color: #004d74;
  letter-spacing: 1px;
  margin-bottom: 0;
  padding: 10px 0;
}

.hcp-strapline-2 p {
  font-size: 17px;
  line-height: 41px;
  font-weight: bold;
  color: #004d74;
  letter-spacing: 1px;
}

#effica {
  height: 0px;
  margin: 1px;
  padding: 1px;
}

#safe {
  height: 0px;
  margin: 1px;
  padding: 1px;
}

.home-banner h1 {
  font-family: "HelveticaHeavy", 'Open Sans', sans-serif;
  font-style: italic;
  font-weight: 800;
  font-size: 110px;
  line-height: 100px;
  color: #004d74;
  text-align: right;
  padding-right: 42%;
  padding-top: 2%;
}

.home-banner h1 span {
  color: #b2d234;
}

h1 {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  font-weight: bold;
}

h2 {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  color: #004d74;
  font-weight: bold;
  font-size: 40px;
  line-height: 49px;
}

h3 {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  color: #004d74;
  font-weight: bold;
  font-size: 24px;
  line-height: 29px;
}

h3 span {
  font-size: 32px;
  line-height: 39px;
}

h4 {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  color: #004d74;
  font-weight: bold;
  font-size: 20px;
  line-height: 26px;
}

h4 span {
  font-family: "HelveticaNeue-Roman", 'Open Sans', sans-serif;
  font-style: italic;
  font-weight: 400;
}

h5 {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  color: #004d74;
  font-weight: 400;
  font-size: 24px;
  line-height: 29px;
}

h6 {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  color: #004d74;
  font-weight: bold;
  font-size: 16px;
  line-height: 19px;
}

.form-section {
  background: #F5F5F5;
}

.nav-pills>li>a {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  ;
  color: #004D74;
  font-size: 20px;
  font-weight: bold;
  border-radius: 0;
  border-bottom: 8px solid transparent;
  margin-bottom: -3px;
  padding: 20px;
}

.nav-pills>li>a:hover,
.nav-pills>li.active>a:hover {
  border-bottom: 8px solid #B2D234;
}

.nav-pills>li.active>a,
.nav-pills>li.active>a:focus,
.nav-pills>li.active>a:hover {
  color: #004D74;
  font-weight: bold;
  border-bottom: 8px solid #B2D234;
}

.nav-pills {
  border-bottom: 0;
}

.wrap-tab-container ul.tab-list li.tab-list-element:nth-child(1) {
  background: #fff;
  background-image: url("/content/dam/open-digital/lynparza/en/submit-icon.svg");
  background-repeat: no-repeat;
  background-position-x: 20px;
  background-position-y: 20px;
}

.wrap-tab-container ul.tab-list li.tab-list-element:nth-child(2) {
  background: #fff;
  background-image: url("/content/dam/open-digital/lynparza/en/submit-icon.svg");
  background-repeat: no-repeat;
  background-position-x: 20px;
  background-position-y: 20px;
}

.wrap-tab-container ul.tab-list li.tab-list-element:nth-child(3) {
  background: #fff;
  background-image: url("/content/dam/open-digital/lynparza/en/speak-icon.svg");
  background-repeat: no-repeat;
  background-position-x: 20px;
  background-position-y: 20px;
}

img.header-nav-logo {
  height: 70px;
  margin-top: 20px;
}

.logo-medicine-txt {
  display: none;
}

.primary-navigation {
  border-bottom: 0;
}

.navbar-default .top-header {
  border-bottom: 0;
}

nav .primary-navigation .nav {
  position: absolute;
  right: -40%;
}

.top-header .navbar-brand {
  height: 80px;
}

/*dropdown*/
.dropdown button,
input,
select,
textarea {
  font-family: inherit;
  border-radius: 35px;
  padding: 10px;
  width: 100%;
  margin-top: 15px;
  font-size: inherit;
  line-height: inherit;
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
  font-size: 18px;
  font-style: normal;
  border: 2px solid #004D74;
  /* margin-left: 10px; */
  color: #004D74;
  border-radius: 50px;
  padding: 12px 27px;
  text-align: center;
  background: rgba(0, 0, 0, 0);
  font-weight: 600;
  text-shadow: none;
  margin-left: 0px;
}

.text.parbase a:hover {
  text-decoration: none;
  background: none;
  color: #004D74;
}

img.imgdownload {
  width: 20px;
  margin-left: 5px;
}

.dropdown button:hover {
  color: #B2D234;
  background-color: #004D74;
}

.dropdown button:active {
  color: #B2D234;
  background-color: #004D74;
}

.dropdown input,
button,
select,
textarea:before {
  content: url(/content/dam/open-digital/lynparza/en/download-icon.svg);
  /*width: 20px;*/
  display: block;
  margin-left: 10px;
}

/*.dropdown input, button, select, textarea:hover {*/
/*    background:orange;*/
/*background-color: rgba(0,0,0,0);*/
/*}*/
.dropdown {
  display: inline-block;
  position: relative;
  height: auto;
}

.dropdown-content:hover {
  background: #fff;
  color: #000;
}

.dropdown-content {
  display: none;
  position: absolute;
  width: 100%;
  background: #fff;
  border-top-left-radius: 20px;
  z-index: 3;
  border-bottom-left-radius: 20px;
  border-bottom-right-radius: 20px;
  overflow: auto;
  padding: 4px 0;
  margin-top: 0px;
  border-top-right-radius: 20px;
  box-shadow: 0px 6px 8px 0px rgba(0, 0, 0, 0.2);
}

.dropdown:hover .dropdown-content {
  display: block;
}

.dropdown-content a {
  display: block;
  color: #555;
  padding: 1.5px;
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
  font-size: 14px;
  font-weight: bold !important;
  text-decoration: none;
}

.dropdown-content a:hover {
  color: #ffffff;
  background-color: #00a4bd;
}

/*dropdown ends here*/
.primary-navigation .nav>li a {
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
  letter-spacing: 0;
  color: #004d74;
  font-weight: 700;
}

.primary-navigation .navbar-nav .open .dropdown-menu>li a.parent-link {
  display: none;
}

.menu-snippet-desktop {
  position: relative;
  right: -80%;
  top: -73px;
}

.reported {
  display: block;
}

.reported1 {
  display: block;
}

#note_text p {
  text-align: left;
  font-size: 16px;
  color: #004d74;
  margin: 30px 0 19px 0;
}

#lynparza-col2 h4 {
  margin-left: -10px;
  margin-right: -50px;
}

#lynparza-col2 ul {
  margin-left: -10px;
}

.glyphicon {
  top: 3px;
}

.footer-image .new-image-desktop {
  background: #F5F5F5;
}

#study-design #solo1-safety-box {
  width: 97%;
}

.footer {
  color: #004d74;
  background: #fff;
}

.footer a,
.footer p {
  color: #004d74;
  font-size: 16px;
}

.footer .copyright-cols .column-1 {
  width: 27%;
  padding-right: 0;
}

.footer .copyright-cols .column-2 {
  width: 46%;
}

.footer .copyright-cols .column-3 {
  width: 27%;
  padding-left: 0;
}

.footer-reference {
  display: none;
}

.home-banner {
  height: 478px;
  text-transform: uppercase;
  background-position: center;
}

.generic-banner {
  height: 232px;
}

.generic-banner-sub {
  position: relative;
  height: 232px;
  top: 65px;
  background-position: bottom;
}

.pi-link .action-link {
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
  margin: 5px auto;
  font-size: 16px;
  line-height: 18px;
  border: 1px solid #B2D234;
  border-radius: 50px;
  padding: 3px 12px 6px 12px;
  width: 100%;
  text-align: center;
  color: #004d74;
  background: #fff;
  text-decoration: none !important;
}

.pi-link .action-link:hover {
  background: #B2D234;
  text-decoration: none !important;
}

.sub-nav {
  position: fixed;
  z-index: 3;
  background: #F5F5F5;
  text-align: center;
  padding-top: 20px;
  top: 147px;
}

.banner-strapline {
  background: #004D74;
  color: #fff;
  padding: 30px 0 30px;
  text-align: center;
}

.banner-strapline h1 {
  font-size: 32px;
  line-height: 38px;
  color: #fff;
  max-width: 93%;
  margin: auto;
}

.licence {
  padding-top: 20px;
}

.banner-strapline h1 span {
  color: #B2D234;
}

.title-bar {
  background: #004D74;
  padding: 30px 0;
}

.title-bar.funding {
  padding: 50px 0 10px;
  margin-top: 41px !important;
}

.title-bar.topMargin {
  margin-top: 70px;
}

.resources .title-bar.topMargin {
  margin-top: 114px;
}

.title-bar h1 {
  color: #B2D234;
  font-size: 42px;
  line-height: 30px;
}

.title-bar.funding h1 {
  margin-top: 35px;
}

.title-bar .col-sm-3.column-1 {
  width: 10%;
}

.title-bar .col-sm-3.column-2 {
  width: 90%;
}

.container-fluid {
  padding-right: 0;
  padding-left: 0;
}

.home-section-a {
  background: #004d74;
  color: #fff;
  text-align: center;
  padding: 37px;
}

.home-section-a h2 {
  font-size: 26px;
  line-height: 31px;
  margin: 0;
  color: #fff;
}

.home-section-a h2 span {
  color: #B2D234;
}

.home-section-b {
  text-align: center;
  padding: 100px 0;
}

.home-section-b h2 {
  font-size: 32px;
  line-height: 38px;
  color: #004D74;
  font-style: oblique;
  text-align: left;
}

.home-section-c {
  text-align: center;
  background: #F5F5F5;
  padding: 20px;
}

.home-section-d {
  padding: 100px 0;
}

.home-section-d h2 {
  font-size: 32px;
  line-height: 38px;
  color: #004D74;
}

.home-section-e {
  text-align: center;
  background: #F5F5F5;
  padding: 80px 0;
}

.home-section-e h3,
.home-section-refs h3 {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif !important;
  color: #004D74;
  font-size: 28px;
  font-weight: bold;
  line-height: 34px;
}

.home-section-e .multi-column-container .col-sm-4.column-1 {
  width: 32%;
  background: #fff;
  padding: 50px 0;
  margin-right: 2%;
}

.home-section-e .multi-column-container .col-sm-4.column-2 {
  width: 32%;
  background: #fff;
  padding: 50px 0;
  margin-right: 2%;
}

.home-section-e .multi-column-container .col-sm-4.column-3 {
  width: 32%;
  background: #fff;
  padding: 50px 0;
}

.home-section-e .multi-column-container .col-sm-6.column-1 {
  width: 49%;
  background: #fff;
  padding: 50px 0;
  margin-right: 2%;
}

.home-section-e .multi-column-container .col-sm-6.column-2 {
  width: 49%;
  background: #fff;
  padding: 50px 0;
}

.home-section-refs h4 {
  font-family: 'Open Sans', sans-serif;
  color: #004D74;
  font-size: 18px;
  line-height: 21px;
  font-weight: bold;
}

.home-section-refs b {
  font-family: 'Open Sans', sans-serif;
  color: #004D74;
  font-size: 16px;
  line-height: 19px;
  font-weight: bold;
}

.footer {
  background: #F5F5F5;
}

.footer p {
  font-size: 16px;
}

.nav-pills {
  display: none;
}

.btn-secondary,
.modal-footer .btn.btn-default,
.form-group .submit-btn {
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
  font-size: 18px;
  font-style: normal;
  border: 2px solid #004D74;
  color: #004D74;
  border-radius: 50px;
  padding: 12px 27px;
  text-align: center;
  background: #fff;
  font-weight: 600;
  text-shadow: none;
}

.btn-secondary:hover,
.form-group .submit-btn:hover {
  color: #B2D234;
  background-color: #004D74;
  border-color: #004D74;
}

.modal-footer .btn.btn-primary {
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
  font-size: 18px;
  font-style: normal;
  font-weight: 700;
  border: 2px solid #004D74;
  color: #004D74;
  border-radius: 50px;
  padding: 12px 27px;
  text-align: center;
  background: #B2D234;
  text-shadow: none;
}

.modal-footer {
  text-align: center;
  border-top: 0;
}

.modal-header {
  border-bottom: 0;
}

.modal-content {
  text-align: center;
  padding: 10px;
}

.modal-title,
.modal-title strong {
  font-size: 24px !important;
  color: #004D74;
}

.glyphicon-chevron-right:before {
  content: url(/content/dam/open-digital/lynparza/en/arrow-r.svg);
  width: 20px;
  display: block;
  margin-left: 10px;
}

.download .glyphicon-chevron-right:before {
  content: url(/content/dam/open-digital/lynparza/en/download-icon.svg);
  width: 20px;
  display: block;
  margin-left: 10px;
}

.download-biomarker-journey-records ul li a {
  padding-left: 10px;
}

.download-biomarker-journey-records .glyphicon-chevron-right:before {
  content: url(/content/dam/open-digital/lynparza/en/play-icon-green.png);
  width: 20px;
  height: 0px;
  display: block;
  margin-top: -3px;
  margin-left: 8px;
  transform: scale(0.02);
}

.study-section {
  text-align: center;
  padding: 60px 0;
}

.efficacy-section {
  text-align: center;
  background: #F5F5F5;
  padding: 60px 0;
}

.safety-section {
  text-align: center;
  padding-top: 60px;
  padding-bottom: 60px;
}

.cta-blue {
  background: #004D74;
  padding: 25px;
  margin: 20px auto;
}

.cta-blue h4 {
  font-size: 22px;
  line-height: 29px;
  color: #fff;
}

.sub-nav .action-link {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif !important;
  color: #004d74;
  font-weight: bold;
  font-size: 20px;
  margin: 0 50px;
}

.accordion-container .panel-default {
  border: 2px solid #004D74;
  border-radius: 30px;
  padding: 10px;
}

.accordion-inner-container .panel-group {
  border-top: 0;
}

.accordion-container .az-panel-heading a {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif !important;
  font-style: normal;
  color: #004D74;
  font-size: 28px;
  text-align: center;
  text-decoration: none;
  display: inline-block;
}

.fa.pull-right {
  color: #B2D234;
}

.action-link .link-txt {
  text-decoration: none !important;
}

.blue-overlay {
  height: 20px;
  padding: 0;
  background: #004d74;
  opacity: 0.5;
  margin-top: -20px;
}

.blue-overlay-sub {
  height: 20px;
  padding: 0;
  background: #004d74;
  opacity: 0.5;
  margin-top: 45px;
}

.navbar-header .new-image {
  width: 190px;
  margin-top: 30px;
}

.download-section {
  padding: 60px 0;
  text-align: center;
}

.resources .download-section {
  padding: 110px 0 60px 0;
  text-align: center;
}

.download-section2 {
  background: #F5F5F5;
  padding: 60px 0;
  text-align: center;
}

.resources .download-section2 {
  background: #F5F5F5;
  padding: 110px 0 60px;
  text-align: center;
}

.expert-section {
  padding: 60px 0;
}

.resources .expert-section {
  padding: 100px 0 60px;
}

.error-section {
  text-align: center;
}

.gr-bullet li {
  list-style: none;
  list-style-image: url("/content/dam/open-digital/lynparza/en/bullet.svg");
}

.title-cols .column-1 {
  width: 25%;
  padding-top: 18px;
}

.title-cols .column-2 {
  width: 75%;
  padding: 0;
}

.title-cols .column-2 p {
  font-size: 26.0px;
  line-height: 40.0px;
  font-weight: bold;
  color: #fff;
}

.hrd-section {
  text-align: center;
  padding: 50px 0;
}

.hrd-section-grey {
  text-align: center;
  padding: 50px 0;
  background: #F5F5F5;
}

.hrd-cols .column-1 {
  padding-top: 20px;
}

.adverse-box {
  text-align: center;
  border: 4.0px solid #fff;
  padding: 20px;
  font-size: 16px;
  margin: 30px 20px;
}

.video-thumb-parent .video-play-icon {
  display: none;
}

.legal h2 {
  color: #004D74;
  font-size: 18px;
  margin: 0;
}

.legal a {
  color: #158FC4;
}

.form-container h2 {
  display: none;
}

.tab-container {
  background: #fff;
}

.wrap-tab-container ul.tab-list {
  border-spacing: 0;
}

.form-wrapper {
  background: #fff;
  padding: 40px;
  border-top: 7px solid #B2D234;
}

.form-header {
  background: #fff;
  padding: 20px;
}

.form-header h3 {
  margin-top: 10px;
}

.form-group .clear-btn {
  display: none !important;
}

.form-control {
  border: 0;
  background: #F5F5F5;
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
  font-size: 16px;
}

.form-control:focus {
  border: 0;
  border-left: 0;
}

label {
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
  font-size: 16px;
  font-weight: 700;
}

.text.parbase a {
  text-decoration: none;
}

.primary-navigation .nav>li.item-more .more-text {
  display: none;
}

.navbar-default .navbar-nav>.open>a,
.navbar-default .navbar-nav>.open>a:hover,
.navbar-default .navbar-nav>.open>a:focus {
  background: none;
}

.breast-cancer-exit-msg {
  display: none;
}

.landing-page .breast-cancer-exit-msg {
  display: block !important;
}

.landing-page .ovarian-cancer-exit-msg {
  display: none !important;
}

.landing-page .self-certification-holder .modal-header {
  display: none;
}

/*newpage*/

.landmark {
  max-width: 779px;
  margin: auto;
}

.patient-characteristics {
  padding-bottom: 20px;
}

h2.efficacy {
  font-weight: bold;
  font-size: 40px;
  line-height: 45px;
  margin-top: 0px;
  margin-bottom: 0px;
}

h3.analysis {
  font-size: 36px;
  line-height: 42px;
  padding-bottom: 12px;
}

h3.reached {
  font-size: 28px;
  line-height: 33px;
}

.green-button:hover {
  background-color: #fff;
}

.green-button1:hover {
  background-color: #fff;
}

.green-button {
  /*font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;*/
  margin: 5px auto;
  font-size: 20px;
  line-height: 29px;
  font-family: "Helvetica";
  border: 1px solid #B2D234;
  border-radius: 50px;
  padding: 20px 0px;
  text-align: center;
  color: #004d74;
  width: 53%;
  background-color: #B2D234;
  margin-bottom: 45px;
  cursor: pointer;
}

.green-button1 {
  /*font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;*/
  margin: 5px auto;
  font-size: 20px;
  line-height: 29px;
  font-family: "Helvetica";
  border: 1px solid #B2D234;
  border-radius: 50px;
  padding: 20px 0px;
  text-align: center;
  color: #004d74;
  width: 53%;
  font-weight: bold;
  background-color: #B2D234;
  margin-bottom: 45px;
  cursor: pointer;
}

.progression {
  font-size: 20px;
  line-height: 24px;
  font-family: "Helvetica";
  color: #004D74;
  text-align: left !important;
}

.progress {
  font-size: 20px;
  line-height: 24px;
  font-family: "Helvetica";
  color: #004D74 !important;
  font-weight: bold;
  background-color: unset;
  box-shadow: unset;
}

.accordion-group.panel {
  border: unset;
  box-shadow: unset;
}

.graph-image .expand-img-desktop {
  background: white;
}

.graph-image .expand-img-mobile {
  background: white;
}

.patient-characteristics .expand-img-desktop {
  background: white;
}

.patient-characteristics .expand-img-mobile {
  background: white;
}

.safety-adverse-events .expand-img-mobile {
  margin-left: 6px;
}

#study-design .accordion-group.panel {
  width: 100%;
}

.months {
  width: 80%;
  text-align: center;
  margin: 0px auto;
}

.alive {
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
  font-size: 24px;
  line-height: 29px;
  width: 77%;
  color: #FFFFFF;
  margin: auto;
  text-align: center;
  font-weight: normal;
}

.placebo {
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
  font-size: 24px;
  line-height: 29px;
  width: 92%;
  color: #FFFFFF;
  margin: auto;
  text-align: center;
  font-weight: normal;
}

#lymparza-women {
  width: 96%;
  background-color: #004D74;
  margin-top: 25px;
  margin-left: 0px;
  padding: 30px 0px 30px;
}

#lymparza-group {
  width: 96%;
  background-color: #004D74;
  margin-top: 25px;
  margin-right: 0px;
  padding: 16px;
}

.safety {
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
  font-size: 28px;
  line-height: 33px;
  width: 93%;
  color: #B2D234;
}

.tablets {
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
  font-size: 20px;
  line-height: 24px;
  width: 92%;
  color: #004D74;
  text-align: left;
  margin: auto;
}

#treatment {
  background-color: #B2D234;
  padding: 20px;
  border-radius: 15px;
  width: 92%;
  margin-left: 0px;
}

.long-button {
  margin: 30px auto;
  font-size: 20px;
  line-height: 29px;
  font-family: "Helvetica";
  border: 1px solid #B2D234;
  border-radius: 50px;
  padding: 20px 0px;
  text-align: center;
  color: #004d74;
  width: 100%;
  background-color: #B2D234;
  margin-bottom: 30px;
  cursor: pointer;
}

.primary-data {
  font-size: 20px;
  line-height: 28px;
  font-family: "Helvetica" !important;
  text-align: left;
  color: #004D74;
  margin-bottom: 0px;
}

.blue-line {
  height: 2px;
  background-color: #004D74;
}

.tumors {
  font-size: 20px;
  line-height: 24px;
  font-family: "Helvetica" !important;
  color: #004D74;
}

#follow-up {
  background-color: #F5F5F5;
  border: 1px solid #F5F5F5;
}

#effic {
  background: #F5F5F5;
  padding: 20px 0;
}

.desktop1 {
  font-size: 28px;
  line-height: 33px;
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  margin: 0px auto 30px;
  /*width: 71%;*/
  ;
}


/*poala page*/

.hype {
  text-decoration: underline !important;
}

.new-added-margin-paola {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  color: #004d74;
  font-weight: bold;
  font-size: 25px;
  line-height: 30px;
  padding-bottom: 10px;
}

.trail {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  color: #004d74;
  font-weight: bold;
  font-size: 28px;
  line-height: 33px;
}

.potential {
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
  font-size: 16px;
  line-height: 20px;
  color: #000000;
  text-align: left;
}

.analysis {
  padding-top: 20px;
}

.can-cer {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  color: #004d74;
  font-weight: bold;
  font-size: 28px;
  line-height: 33px;
}

.undergo {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  color: #000000;
  font-weight: bold;
  font-size: 28px;
  line-height: 33px;
  text-align: left;
}

.surgery {
  padding-top: 20px;
}

.year-graph {
  width: 96%;
  margin-left: 24.5px;
}

.hrd-positive {
  text-align: center;
  background: #F5F5F5;
  padding: 20px 0;
}

.pfs-analysis {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  color: #004D74;
  font-weight: bold;
  font-size: 35px;
  line-height: 42px;
  text-align: center;
}

.subgroup {
  max-width: 90%;
  margin: auto;
  text-align: center !important;
}

.exploratory {
  font-size: 19.5px;
  line-height: 20px;
  font-family: "Helvetica";
  color: #004D74 !important;
  font-weight: bold;
  background-color: unset;
  box-shadow: unset;
  text-align: left;
}

.explorat {
  font-size: 19.5px;
  line-height: 20px;
  font-family: "Helvetica";
  color: #004D74 !important;
  background-color: unset;
  box-shadow: unset;
  font-weight: normal;
  text-align: left;
}

.stati {
  padding-top: 20px;
}

#hrd-positive {
  background-color: #f5f5f5;
  padding-bottom: 25px;
}

#hrd-positive .accordion-container .az-panel-heading a {
  font-size: 35px;
  line-height: 42px;
  text-align: center;
  margin-top: 10px;
  margin-bottom: 10px;
}

#hrd-positive .accordion-container .panel-default {
  background-color: #f5f5f5;
}

.achieve {
  padding-top: 20px;
  width: 86%;
  margin: auto;
}

.achiever {
  padding-top: 20px;
  width: 86%;
  margin: auto;
}

.inhibitor {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  font-size: 24px;
  line-height: 29px;
  text-align: center;
  padding: 15px 40px;
  background-color: #004D74;
  color: #ffffff;
  margin-top: 20px;
}

.bevacizumab {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  font-size: 40px;
  color: #004D74;
  line-height: 48px;
  text-align: center;
}

.remain {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  font-size: 28px;
  line-height: 33px;
  text-align: center;
  padding: 15px 50px;
  background-color: #004D74;
  color: #ffffff;
  margin-top: 25px;
}

div #section-mid {
  width: 95.5%;
}

.product {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  font-size: 20px;
  line-height: 28px;
  text-align: left;
  margin-bottom: 30px;
}

.ctcae {
  padding-top: 0px;
}

.graded {
  font-family: "HelveticaNeue", 'Open Sans', sans-serif;
  font-size: 17px;
  line-height: 20px;
  text-align: left;
}

.signals {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  font-size: 28px;
  line-height: 33px;
  text-align: center;
  background-color: #B2D234;
  color: #004D74;
  padding: 15px 125px;
  margin-top: 80px;
}

#dose-mod {
  background-color: #ffffff;
}

#hrd-positive .fa.pull-right {
  color: #B2D234;
  position: absolute;
  right: 60px;
}

#dose-mod .fa.pull-right {
  color: #B2D234;
  position: absolute;
  right: 60px;
  top: 25px;
}

#dose-mod .az-panel-heading {
  position: relative;
}

#dose-mod .az-panel-heading a {
  font-size: 35px;
  line-height: 42px;
  text-align: center;
  margin-top: 10px;
  padding: 0px 122px;
  margin-bottom: 10px;
}

#section-mid .line {
  height: 2px;
  background-color: #004D74;
}

.report {
  padding-top: 10px;
  width: 98%;
  margin: auto;
}

.specified {
  font-size: 19.7px;
  line-height: 24px;
  font-family: "Helvetica";
  color: #004D74 !important;
  background-color: unset;
  box-shadow: unset;
  font-weight: normal;
  text-align: left;
}

ul.gr-bullet {
  margin-left: -22px;
  max-width: 95%;
}

.ecog-text {
  padding-top: 20px;
}

.study-sec {
  text-align: center;
  padding: 60px 0 30px;
}

.managed {
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
  font-size: 28px;
  line-height: 33px;
  text-align: center;
  padding: 15px 60px;
  background-color: #004D74;
  color: #ffffff;
  margin-top: 25px;
}

.refer-ence {
  padding-bottom: 10px;
}

sub,
sup {
  font-size: 62%;
}

.sm-text ol li {
  font-size: 17px !important;
  line-height: 20px !important;
  padding-bottom: 10px !important;
}

.plastic {
  font-size: 17px !important;
  line-height: 20px !important;
  padding-top: 10px !important;
  max-width: 97%;
}

#patient-enrollment .fa.pull-right {
  color: #B2D234;
  position: absolute;
  right: 60px;
}

#footer-sec p {
  font-family: "HelveticaNeue-Medium", 'Open Sans', sans-serif !important;
}


/*poala end*/

#popup-template.modal {
  overflow: auto;
}

.p-popup__body-cards {
  display: flex;
  justify-content: center;
  align-items: center;
}

.p-popup__card p {
  line-height: normal!important;
  font-weight: bold;
  font-size: 11px!important;
}

.p-popup__header-img {
  display: none;
}

.p-popup__footer {
  display: flex;
  flex-direction: column;
  padding: 0 20px 20px;
}

p.bottom-jbn {
  max-width: 1400px;
  margin: 0 auto;
  padding: 0 15px;
}

@media screen and (max-width:1199px) {
  .home-banner h1 {
    font-size: 95px;
    line-height: 90px;
    color: #004d74;
    text-align: right;
    padding-right: 40%;
    padding-top: 5%;
  }
}

@media screen and (max-width:1270px) {
  nav .primary-navigation .nav {
    right: -36%;
  }
}

@media screen and (max-width:1130px) {
  nav .primary-navigation .nav {
    right: -33%;
  }
}

@media screen and (max-width:1024px) {
  nav .primary-navigation .nav {
    right: -28%;
  }
}

@media screen and (max-width:767px) {

  .hcp-strapline-2 {
    height: 41px;
    padding: 5px 0;
  }

  .hcp-strapline p {
    padding: 0;
  }

  .hcp-strapline-2 {
    top: 65px;
  }

  /*.hcp-strapline p {
    font-size: 14px;
    line-height: 16px !important;
  }*/

  .hcp-strapline p, .hcp-strapline-2 p {
    font-size: 11px;
    line-height: 16px !important;
    letter-spacing: normal;
  }

  .title-bar.funding h1 {
    margin-top: 20px;
  }

  .resources .hcp-strapline {
    top: 81px;
  }

  /*dropdown starts here*/
  .dropdown-content {
    display: none;
    position: absolute;
    width: 100%;
    border-top-left-radius: 20px;
    overflow: auto;
    margin-top: 4px;
    z-index: 3;
    background: #fff;
    /* z-index: 1; */
    border-top-right-radius: 20px;
    box-shadow: 0px 10px 10px 0px rgba(0, 0, 0, 0.4);
  }

  /*dropdown ends here*/

  nav .primary-navigation .nav {
    right: 4%;
  }

  .landmark {
    font-size: 22px;
    line-height: 26px;
    text-align: center !important;
  }

  .study-section {
    text-align: center;
    padding: 20px 0;
  }

  .desktop1 {
    font-size: 20px;
    line-height: 24px;
    font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
    margin: 0px auto 30px;
    width: 100%;
    padding: 10px 35px 0 35px;
  }

  #lynparza-col2 h4 {
    margin-left: 0px;
    margin-right: 0px;
  }

  #study-design #solo1-safety-box {
    width: 100%;
  }



  /*poala-page*/

  .hype {
    text-decoration: underline !important;
  }

  span.hyper {
    text-decoration: underline;
  }

  .banner-strapline {
    background: #004D74;
    color: #fff;
    padding: 20px 0 22px;
    text-align: center;
  }

  .banner-strapline h1 {
    font-size: 22px;
    line-height: 27px;
    max-width: 81%;
  }

  .new-added-margin-paola {
    font-size: 18px;
    line-height: 21px;
    max-width: 70%;
    margin: auto;
  }

  #study-design h2 {
    padding-top: 0px !important;
    font-size: 26px;
    line-height: 32px;
  }

  .trail {
    font-size: 20px;
    line-height: 24px;
    max-width: 94%;
    margin-left: auto;
    margin-right: auto;
  }

  .hidd-en {
    display: none;
  }

  .text-right {
    display: none;
  }

  .spac {
    height: 6px;
  }

  .potential {
    font-size: 9px !important;
    line-height: 12px !important;
  }

  .can-cer {
    font-weight: bold;
    font-size: 14px;
    line-height: 18px;
    margin-top: 0px;
    max-width: 95%;
  }

  .year-graph {
    width: 96%;
    margin: auto !important;
  }

  .study-sec {
    text-align: center;
    padding: 60px 0 20px;
  }

  #section-mid h2 {
    font-size: 26px;
    line-height: 32px;
    margin-top: 5px;
  }

  #section-mid .pfs-analysis {
    max-width: 80%;
    margin: 10px auto 0px;
  }

  .pfs-analysis {
    font-size: 20px;
    line-height: 25px;
    margin-top: 10px;
  }

  .mob-spa {
    margin-bottom: 20px;
    margin-top: 0px;
  }

  .spac-ing {
    height: 16px;
  }

  .green-button1 {
    margin: 5px auto;
    font-size: 12px;
    line-height: 14px;
    font-family: "Helvetica";
    border: 1px solid #B2D234;
    border-radius: 27px;
    padding: 10px 0px;
    text-align: center;
    color: #004d74;
    font-weight: bold;
    width: 100%;
    background-color: #B2D234;
    margin-bottom: 30px !important;
    cursor: pointer;
  }

  .exploratory {
    font-size: 9px;
    line-height: 12px;
    margin: 4px 0px 0px 0px;
  }

  .explorat {
    font-size: 9px;
    line-height: 12px;
    margin: 0px 0px 10px 0px;
  }

  .stati {
    padding-top: 10px;
  }

  #patient-enrollment .panel-body {
    padding: 15px 8px;
  }

  #patient-enrollment .fa.pull-right {
    color: #B2D234;
    position: absolute;
    right: 16px;
    top: 23px;
  }

  .accordion-group {
    position: relative;
  }

  #patient-enrollment .panel-default {
    border-radius: 20px !important;
  }

  #patient-enrollment .accordion-container .panel-default {
    padding: 0px !important;
  }

  #hrd-positive .accordion-container .az-panel-heading a {
    font-size: 20px;
    line-height: 25px;
    text-align: center;
    margin-top: 0px;
    margin-bottom: 0px;
    max-width: 90%;
  }

  #hrd-positive .accordion-container .panel-default {
    padding: 0px !important;
  }

  #hrd-positive .panel-body {
    padding: 10px 8px 0px;
  }

  #hrd-positive .fa.pull-right {
    color: #B2D234;
    position: absolute;
    right: 16px;
    top: 15px;
  }

  #hrd-positive {
    background-color: #f5f5f5;
    padding-bottom: 10px;
  }

  #hrd-positive .panel-default {
    border-radius: 20px !important;
  }

  #hrd-positive .accordion-inner-container {
    padding-top: 0px !important;
  }

  .achieve {
    padding-top: 15px;
    width: 92%;
    margin: auto;
  }

  .achiever {
    padding-top: 15px;
    width: 95%;
    margin: auto;
  }

  .inhibitor {
    font-size: 16px;
    line-height: 20px;
    text-align: center;
    padding: 15px 15px;
  }

  .subgroup {
    max-width: 100% !important;
  }

  .bevacizumab {
    font-size: 26px;
    line-height: 32px;
  }

  .safety-section {
    text-align: center;
    padding: 25px 0px 25px !important;
  }

  .remain {
    font-size: 16px;
    line-height: 20px;
    padding: 15px 10px;
    margin-top: 25px;
    margin-bottom: 10px;
  }

  div #section-mid {
    width: 100%;
    padding: 10px;
  }

  .patients {
    max-width: 92%;
    margin: 0px auto;
    margin-bottom: 10px;
  }

  .product {
    font-size: 9px;
    line-height: 12px;
    text-align: left;
    margin-bottom: 10px;
    margin-top: 0px;
  }

  .graded {
    font-size: 9px !important;
    line-height: 12px !important;
    text-align: left;
    margin-bottom: 0px;
  }

  .ctcae {
    padding-top: 0px;
  }

  .signals {
    font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
    font-size: 16px;
    line-height: 20px;
    padding: 15px 0px;
    margin-top: 40px;
    margin-bottom: 10px;
  }

  #dose-mod .az-panel-heading a {
    font-size: 20px;
    line-height: 25px;
    text-align: center;
    margin-top: 0px;
    margin-bottom: 0px;
    max-width: 80%;
    padding: 0px !important;
  }

  #dose-mod .panel-default {
    border-radius: 20px !important;
  }

  #dose-mod .panel-default {
    padding: 0px !important;
  }

  #dose-mod .panel-body {
    padding: 4px 8px;
  }

  #dose-mod .fa.pull-right {
    color: #B2D234;
    position: absolute;
    right: 16px;
    top: 13px;
  }

  .managed {
    font-size: 16px;
    line-height: 20px;
    padding: 15px 20px;
    margin-top: 15px;
    margin-bottom: 6px;
  }

  .report {
    font-weight: bold;
    font-size: 26px;
    line-height: 32px;
    padding-top: 0px;
    width: 100%;
    margin: auto;
  }

  .specified {
    font-size: 14px;
    line-height: 18px;
    text-align: center !important;
    max-width: 90%;
    margin: 0px auto 18px;
  }

  .home-section-e {
    padding: 20px 0px 38px !important;
  }

  #events h3 {
    font-size: 28px;
    line-height: 33px;
    text-align: center;
    margin-top: 5px;
  }

  #tablets h3 {
    font-size: 26px;
    line-height: 32px;
    text-align: center;
    margin-top: 0px;
    margin-bottom: 15px;
  }

  #tablets h4 {
    font-size: 16px;
    line-height: 19px;
    text-align: left;
    margin-top: 0px;
    margin-bottom: 10px;
  }

  .gr-bullet li {
    font-size: 16px !important;
    line-height: 19px !important;
  }

  #tablets p {
    font-size: 16px !important;
    line-height: 19px !important;
    margin-bottom: 0px;
  }

  #tablets .sm-text ol li {
    font-size: 12px !important;
    line-height: 14px !important;
  }

  #tablets ol {
    margin-left: -24px !important;
    max-width: 96.2%;
  }

  #tablets .plastic {
    font-size: 12px !important;
    line-height: 14px !important;
  }

  #effica {
    height: 0px;
    margin: 0px !important;
    padding: 13px 0px 13px;
    background: #F5F5F5;
  }

  #safe {
    height: 0px;
    margin: 0px !important;
    padding: 15px 0px 15px;
  }

  .study-sec {
    text-align: center;
    padding: 50px 0 20px;
  }

  .reported {
    display: unset !important;
  }

  .reported1 {
    display: unset !important;
  }
}

@media screen and (max-width:991px) and (min-width:768px) {
  .home-banner h1 {
    font-size: 75px;
    padding-top: 8%;
    padding-right: 37%;
    line-height: 80px;
  }

  .top-header .navbar-brand {
    height: 153px;
  }

  nav .primary-navigation .nav {
    top: 80px;
    left: 135px;
  }

  .menu-snippet-desktop {
    display: block !important;
  }

  .pi-link .action-link {
    font-size: 14px;
    padding: 1px 6px 3px 6px;
  }

  .primary-navigation .nav.stacked-menu .hidden-menu {
    display: block;
  }

  .navbar-header .new-image {
    width: 145px;
  }

  .home-section-d .column-2 {
    padding-right: 20px;
  }

  .sub-nav .action-link {
    margin: 0px 50px 0;
  }

  .resources .sub-nav .action-link {
    font-size: 15px;
    margin: 0px 10px 0;
  }

  .title-cols .column-2 p {
    font-size: 20px;
    line-height: 28px;
  }

  .two-line-title .main-title {
    font-size: 30px;
  }

  .sub-nav {
    top: 124px;
  }

  .reported {
    display: unset !important;
  }

  .reported1 {
    display: unset !important;
  }
}

@media screen and (min-width:992px) and (max-width:1200px) {

  nav .primary-navigation .nav {
    right: -20%;
  }

  .resources .sub-nav .action-link {
    margin: 0px 10px;
  }

  .reported {
    display: unset !important;
  }

  .reported1 {
    display: unset !important;
  }
}

@media screen and (max-width:840px) and (min-width:768px) {
  nav .primary-navigation .nav {
    left: 23px;
  }

  .primary-navigation .nav>li a {
    font-size: 15px;
  }

  .reported {
    display: unset !important;
  }
}

@media screen and (min-width:768px) {
  .mobile {
    display: none;
  }

  .bottom-hover-border:after {
    display: block;
    content: '';
    border-bottom: solid 5px #B2D234;
    transform: scaleX(0);
    transition: transform 250ms ease-in-out;
    position: relative;
    bottom: -8px;
  }

  .bottom-hover-border-blue:after {
    display: block;
    content: '';
    border-bottom: solid 5px #004D74;
    transform: scaleX(0);
    transition: transform 250ms ease-in-out;
    position: relative;
    bottom: -20px;
    text-decoration: none !important;
  }

  .bottom-hover-border-blue:hover:after,
  .bottom-hover-border-blue.active:after {
    text-decoration: none !important;
    transform: scaleX(1);
  }

  .homepage .primary-navigation .nav>li:first-child {
    border-bottom: 5px solid #B2D234;
    padding: 0;
    margin-right: 25px;
  }

  .home-section-d .column-2 {
    padding-right: 147px;
  }

  .p-popup__header-img {
    display: block;
  }

  .p-popup__body-cards {
    flex-direction: row;
  }

  .p-popup__body-cards .p-popup__card:nth-child(2) {
    margin: 0 100px;
  }

  .p-popup__footer {
    flex-direction: row;
    justify-content: space-between;
    align-items: center;
    padding: 0 20px;
  }

  #popup-template .modal-dialog button.close {
    top: 100px;
  }

  .p-popup__card p {
    font-size: 14px !important;
  }

  #popup-template .modal-dialog {
    padding: 10px;
  }

  p.bottom-jbn {
    padding: 0 19px;
  }
}

@media screen and (max-width:767px) {
  .desktop {
    display: none;
  }

  .sub-nav {
    top: 153px;
  }

  .home-banner h1 {
    font-size: 63px;
    line-height: 58px;
    padding-right: 33px;
    padding-top: 0;
    margin: 0;
    display: none;
  }

  .home-section-a h2 {
    font-size: 24px;
    line-height: 29px;
  }

  .home-section-b h2 {
    font-size: 24px;
    line-height: 29px;
    text-align: center;
  }

  .home-section-e {
    padding: 60px 0;
  }

  .paola-text {
    padding: 0 20px 40px 20px;
  }

  .blue-overlay {
    margin-top: -72px;
  }

  .home-section-a {
    padding: 20px;
  }

  .top-header .navbar-brand {
    height: 130px;
  }

  .top-header .header-nav-logo-condensed {
    height: 55px;
  }

  .top-header .navbar-brand {
    padding-top: 20px;
  }

  .navbar-default .navbar-toggle .icon-bar {
    background-color: #004D74;
  }

  .navbar-toggle .icon-bar+.icon-bar {
    margin-top: 5px;
  }

  .navbar-toggle .icon-bar {
    width: 43px;
    height: 5px;
  }

  .navbar-default .top-header .navbar-header .navbar-toggle {
    border-left: 0;
  }

  .navbar-default .navbar-toggle:hover,
  .navbar-default .navbar-toggle:focus {
    background-color: #fff;
  }

  .primary-navigation .nav.stacked-menu {
    background: #004D74;
    color: #fff;
    margin-top: 0;
    width: 100%;
  }

  .primary-navigation .nav>li .dropdown-menu {
    background: #015A88;
  }

  .primary-navigation .nav>li .dropdown-menu a,
  .primary-navigation .nav>li.active>a,
  .primary-navigation .nav>li a {
    color: #b2d234;
  }

  .linked-list.horizontal li {
    margin-right: 0;
    position: relative;
  }

  .btn-secondary {
    width: auto;
  }

  .home-section-e .multi-column-container .col-sm-4.column-1 {
    width: 90%;
    margin: 0 20px 0;
  }

  .home-section-e .multi-column-container .col-sm-4.column-2 {
    width: 90%;
    margin: 20px 20px 0;
  }

  .home-section-e .multi-column-container .col-sm-4.column-3 {
    width: 90%;
    margin: 20px 20px 0;
  }

  .sub-nav .action-link {
    font-size: 13px;
    margin: 0 25px 0 !important;
    text-align: center;
    padding: 0 !important;
    line-height: 16px;
  }

  .banner-strapline h1 {
    font-size: 20px;
    line-height: 24px;
    text-align: center !important;
  }

  h2 {
    font-size: 34px;
    line-height: 37px;
  }

  #study-design h2 {
    padding-top: 25px;
  }

  .navbar-header .new-image {
    width: 155px;
    position: absolute;
    top: -65px;
  }

  .top-header-links li:after {
    display: none !important;
  }

  .pi-link .action-link {
    padding: 4px;
    font-size: 14px;
    border-radius: 7px;
  }

  .cta-blue h4 {
    font-size: 18px;
    line-height: 22px;
  }

  .accordion-container .az-panel-heading a {
    font-size: 20px;
    line-height: 23px;
  }

  h3 {
    font-size: 20px;
    line-height: 24px;
  }

  .homepage .primary-navigation .nav>li:first-child {
    background-color: #B2D234;
    color: #004D74 !important;
  }

  .homepage .primary-navigation .nav>li:first-child a {
    color: #004D74 !important;
  }

  .navbar-default .navbar-nav>.open>a,
  .navbar-default .navbar-nav>.open>a:hover {
    background-color: #003855;
    color: #B2D234 !important;
  }

  .primary-navigation .nav>li>a {
    padding: 15px 0 15px 30px;
    border-left: 0;
    border-bottom: 1px solid #ffffff;
  }

  .primary-navigation .nav li.open>.dropdown-menu>li a {
    padding: 15px 0 15px 40px;
    color: #B2D234;
    border-bottom: 1px solid #ffffff;
  }

  .primary-navigation .nav li.open>.dropdown-menu>li.active a {
    color: #B2D234;
  }

  .primary-navigation .nav>li.open>.dropdown-menu {
    border-top: 0;
    border-bottom: 0;
  }

  .primary-navigation .dropdown-menu .divider {
    background-color: #003855;
    display: none;
  }

  .primary-navigation .nav li.open {
    border-bottom: 0;
  }

  h5 {
    font-weight: bold;
    font-size: 20px;
    line-height: 24px;
  }

  .cta-blue {
    padding: 20px;
  }

  .cta-section .column-2 {
    margin-top: 150px;
  }

  .cta-section h3 {
    font-size: 28px;
    line-height: 34px;
  }

  p,
  b,
  ul li,
  ol li {
    font-size: 17px;
    line-height: 21px !important;
  }

  .tab-container {
    display: none;
  }

  .home-section-a {
    margin-top: -8px;
  }

  .home-section-e .multi-column-container .col-sm-6.column-1 {
    width: 90%;
    background: #fff;
    margin: 20px !important;
  }

  .home-section-e .multi-column-container .col-sm-6.column-2 {
    width: 90%;
    background: #fff;
    margin: 0 20px !important;
  }

  .title-bar .col-xs-12.column-1 {
    width: 25%;
    padding-right: 0;
  }

  .title-bar .col-xs-12.column-2 {
    width: 75%;
  }

  .sm-text p,
  .sm-text ol li {
    font-size: 13px;
  }

  .adverse-box {
    padding: 10px;
  }

  .generic-banner-sub {
    height: 192px;
    background-position: right;
  }

  h3 span {
    font-size: 26px;
    line-height: 31px;
  }

  .title-bar h1 {
    font-size: 38px;
  }

  .title-bar {
    padding: 30px 0 30px 30px;
  }

  .submit-enquiry-cols .col-xs-12.column-1 {
    width: 25%;
  }

  .submit-enquiry-cols .col-xs-12.column-2 {
    width: 75%;
    padding-left: 0;
  }

  .btn-secondary {
    font-size: 16px;
  }

  .accordion-container .panel-default {
    border-radius: 40px;
  }

  .home-banner {
    background-position: top;
  }

  .footer a,
  .footer p {
    font-size: 15px !important;
  }

  .pi-link {
    text-align: center;
    margin-top: -50px;
  }

  .top-header-links {
    width: 100%;
  }

  .top-header .navbar-header {
    height: 160px;
  }

  body.fixed-top-margin {
    margin-top: 160px !important;
  }

  h2.efficacy {
    font-weight: bold;
    font-size: 26px;
    line-height: 31px;
    margin-top: 0px;
    margin-bottom: 0px;
    padding: 0 25px;
  }

  h3.analysis {
    font-size: 20px;
    line-height: 24px;
  }

  .green-button {
    margin: 5px auto;
    font-size: 12px;
    line-height: 14px;
    font-family: "Helvetica";
    border: 1px solid #B2D234;
    border-radius: 27px;
    padding: 10px 0px;
    text-align: center;
    color: #004d74;
    width: 100%;
    background-color: #B2D234;
    margin-bottom: 45px;
    cursor: pointer;
  }

  .progression {
    font-size: 6px;
    line-height: 7px;
    font-family: "Helvetica";
    color: #004D74;
    text-align: left !important;
  }

  .progress {
    font-size: 6px;
    line-height: 7px;
    font-family: "Helvetica";
    color: #004D74 !important;
    font-weight: bold;
  }

  .months {
    width: 100%;
    text-align: center;
    margin: auto;
  }

  h3.reached {
    font-size: 14px;
    line-height: 16px;
    padding: 25px 0;
  }

  h3.reached:nth-child(2) {
    padding: 15px 0;
  }

  #lymparza-women {
    width: 100%;
  }

  #lymparza-group {
    width: 100%;
  }

  .alive {
    font-size: 16px;
    line-height: 18px;
    width: 78%;
  }

  .placebo {
    font-size: 16px;
    line-height: 18px;
    width: 78%;
  }

  .safety {
    font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
    font-size: 14px;
    line-height: 16px;
    width: 100%;
    color: #B2D234;
    padding-bottom: 20px;
  }

  #treatment {
    font-size: 16px;
    line-height: 19px;
    width: 100%;
    margin-top: 20px;
  }

  .tablets {
    font-size: 16px;
    line-height: 19px;
    width: 100%;
  }

  .long-button {
    margin: 20px auto;
    font-size: 12px;
    line-height: 14px;
    border-radius: 25px;
    padding: 10px 16px;
    text-align: center;
    width: 100%;
  }

  .primary-data {
    font-size: 6px;
    line-height: 7px !important;
  }

  .re-mob {
    font-size: 26px !important;
    line-height: 31px !important;
  }

  .tumors {
    font-size: 14px;
    line-height: 16px;
    font-family: "Helvetica" !important;
    color: #004D74;
  }

  .home-section-e h3,
  .home-section-refs h3 {
    text-align: center;
    font-size: 24px;
  }
}

@media screen and (max-width:414px) and (min-width:375px) {
  .primary-navigation .collapse.in .nav.stacked-menu {
    height: 400px;
    overflow: scroll;
  }
}

@media screen and (min-width:992px) {
  body.fixed-top-margin {
    margin-top: 145px !important;
  }
}

@media screen and (max-width:374px) {
  .pi-link .action-link {
    padding: 5px;
    font-size: 12px;
    border-radius: 6px;
  }

  .title-bar h1 {
    font-size: 30px;
  }
}

@media screen and (max-width:767px) {
  nav .primary-navigation {
    position: absolute !important;
    width: 100%;
  }

  .navbar-fixed-top .primary-navigation {
    position: absolute !important;
  }

  .resource-downladable-res-sec-new .col-sm-6.col-xs-12.column-1 {
    margin-bottom: 20px;
  }
}

@media all and (max-width:767px) {
  .title-bar {
    margin-top: 160px;
  }

  .sub-nav {
    margin-top: 0px;
  }

  .title-bar.topMargin {
    margin-top: 0px;
    padding-top: 45px;
  }

  .resources .title-bar.topMargin {
    margin-top: 120px;
  }

  nav .primary-navigation {
    position: absolute !important;
    width: 100%;
  }
}

@media screen and (max-width:991px) and (min-width:768px) {
  body.fixed-top-margin {
    margin-top: 124px !important;
  }

  .hype {
    text-decoration: underline !important;
  }
}

.new-added-margin-paola {
  margin-top: -2.5%;
}

.space {
  color: #ffffff !important;
  padding-left: 1.5px;
}

.new-italic {
  color: #ffffff !important;
  font-style: italic;
}

@media all and (max-width:767px) {
  .new-added-margin-paola {
    margin-top: -9%;
  }
}

.multi-layer-popup {
  background: rgb(0 0 0 / .3);
}

.multi-layer-popup .modal-content {
  background-color: transparent;
  border: none;
  border-radius: 0;
  padding: 0px;
  box-shadow: none;
}

.multi-layer-popup .modal-content .modal-header {
  display: none;
}

.multi-layer-popup .modal-content .modal-body {
  padding: 0px;
}

.multi-layer-popup .event-popup-header {
  position: relative;
  padding: 30px 15px;
  background: #004d74;
}

.multi-layer-popup .close {
  position: absolute;
  top: 5px;
  right: 0px;
  width: 50px;
}

.multi-layer-popup .close .close-symbol {
  display: none;
}

.multi-layer-popup .close .close-icon {
  width: 100%;
}

.multi-layer-popup .event-header-columns {
  max-width: 850px;
  margin: 0 auto;
}

.multi-layer-popup .event-header-columns .column-1 img {
  width: 100%;
  max-width: 350px;
}

.multi-layer-popup .block-elem {
  display: block;
}

.multi-layer-popup .event-time {
  text-align: left;
  font-family: "HelveticaNeue-Bold", 'Open Sans', sans-serif;
}

.multi-layer-popup .event-time .white-txt {
  color: #fff;
}

.multi-layer-popup .event-time .green-txt {
  color: #B2D234;
}

.multi-layer-popup .event-time .hyphen {
  padding-left: 3px;
}

.multi-layer-popup .event-msg-box {
  background: url("/content/dam/open-digital/lynparza/en/oc-summit-22/msg-gradiant-bg.png") no-repeat right top;
  color: #fff;
  font-family: "HelveticaNeue", 'Open Sans', sans-serif;
}

.multi-layer-popup .event-body {
  background: #fff;
  color: #004d74;
  padding: 15px;
  text-align: left;
}

.multi-layer-popup .event-body .body-msg p {
  font-family: 'HelveticaNeue-Medium' !important;
  color: #004d74 !important;
}

.multi-layer-popup .event-body .body-msg .bold-txt {
  font-family: "HelveticaNeue-Bold";
}

.multi-layer-popup .event-body .jbn-row {
  padding: 20px 0 0 0;
}

.multi-layer-popup .jbn-row .gb-dop {
  font-family: "HelveticaNeue", 'Open Sans', sans-serif;
  font-size: 16px;
}

.multi-layer-popup .jbn-row .funded-by-az {
  font-family: "HelveticaNeue-Roman";
  font-size: 15px;
  font-style: italic;
}

.multi-layer-popup .event-footer {
  font-family: "HelveticaNeue-Bold";
  color: #fff;
  background: #fff;
}

.no-wrap {
  white-space: nowrap;
}

.popup-container {
  position: relative;
}

.multi-layer-popup .event-footer {
  padding: 25px 0 40px !important;
  clear: both;
}

.multi-layer-popup .event-footer span.register-now-cta {
  background: #004d74;
  color: #fff;
  border-radius: 40px;
  padding: 20px;
  display: block;
  width: calc(100% - 30px);
  margin: 0 auto;
}

@media all and (max-width:767px) {
  .multi-layer-popup .event-time {
    margin: 25px 0 0 0;
    border-left: none;
    font-size: 35px;
    line-height: 50px;
    max-width: 309px;
    margin: 30px auto 0;
  }

  .multi-layer-popup .event-msg-box {
    background-size: 100% 100%;
    font-size: 20px;
    padding: 15px 15px;
    letter-spacing: .5px;
    line-height: 24px;
  }

  .multi-layer-popup .event-body .body-msg p {
    font-size: 24px;
    line-height: 30px !important;
    margin-bottom: 30px;
    letter-spacing: .5px;
  }

  .multi-layer-popup .jbn-row .funded-by-az,
  .multi-layer-popup .jbn-row .gb-dop {
    padding-bottom: 20px;
  }

  .multi-layer-popup .event-footer {
    background-size: 100% 100%;
    padding: 15px 15px;
    font-size: 24px;
    letter-spacing: 1px;
    line-height: 28px;
  }

  .multi-layer-popup .event-footer span.click-here {
    display: block;
  }

  .multi-layer-popup .event-footer .register-now-cta {
    line-height: 30px;
  }

  .download-biomarker-journey ul {
    display: block;
  }
}

@media screen and (min-width:768px) {
  .multi-layer-popup .modal-dialog {
    max-width: 750px;
  }

  .multi-layer-popup .event-time {
    margin: 55px 0 0 0px;
    border-left: 1px solid #B2D234;
    font-size: 35px;
    line-height: 50px;
    padding-left: 15px;
  }

  .multi-layer-popup .event-msg-box {
    background-size: 100%;
    font-size: 24px;
    padding: 15px 15px;
    letter-spacing: .5px;
  }

  .multi-layer-popup .event-body .body-msg p {
    font-size: 28px;
    line-height: 38px !important;
    margin-bottom: 30px;
    letter-spacing: .5px;
  }

  .multi-layer-popup .jbn-row .gb-dop {
    width: 290px;
    padding-right: 0px;
  }

  .multi-layer-popup .jbn-row .funded-by-az {
    width: calc(100% - 290px);
    padding-left: 0px;
    text-align: right;
  }

  .multi-layer-popup .event-footer {
    background-size: 100%;
    padding: 15px 15px;
    font-size: 32px;
    letter-spacing: 1px;
  }

  .download-biomarker-journey ul {
    display: flex;
  }
}

@media screen and (max-width:991px) and (min-width:768px) {
  .multi-layer-popup .modal-dialog {
    width: calc(100% - 50px);
  }

  .multi-layer-popup .event-time {
    margin: 50px 0 0 0;
    font-size: 35px;
    line-height: 50px;
  }
}

.resource-downladable-res-sec-new-second {
  margin-top: 5%;
}

.download.download-biomarker-journey ul li:nth-child(2) a .glyphicon-chevron-right:before {
  content: "";
}

.thank-you-snipp {
  width: 100%;
}

.snippet-thank-you .modal-md .close span {
  display: none;
}

.snippet-thank-you .modal-dialog {
  margin-top: 20px !important;
}

.snippet-thank-you .modal-body {
  max-height: none !important;
  min-height: auto !important;
  overflow: hidden;
}

.new-snipp-div {
  padding-top: 15px !important;
}

.snippet-thank-you .modal-title {
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
}

.error-page .primary-navigation {
  display: none;
}

.error-page .navbar-default {
  border: 0;
}

.error-page .navbar-default .top-header .navbar-header .navbar-toggle {
  display: none;
}

@media (min-width: 1200px) {
  .container {
    width: 1178px;
  }
}

/*new page*/

@media (min-width: 1920px) {
  .container, {
    width: 1400px;
  }

  .bottom-jbn {
    max-width: 1400px;
  }

  .reported {
    display: unset;
  }

  .reported1 {
    display: block;
  }
}

@media screen and (min-device-width: 1200px) and (max-device-width: 1600px) and (-webkit-min-device-pixel-ratio: 1) {
}

_::-webkit-full-page-media,
_:future,
:root .fixed-top-margin {
  width: auto;
}

/*landing page starts*/

.landing-page-wrapper {
  background: #F5F5F5;
  text-align: center;
  padding-bottom: 60px;
}

.landing-page-hcp-strapline {
  background: #E4F2FA;
  text-align: center;
  padding: 18px 0 10px 0;
}

.landing-page-hcp-strapline p {
  color: #3F4444;
  font-size: 15px;
}

.landing-page-cta {
  width: 394px;
}

.landing-page h1 {
  color: #004D74;
  font-size: 32px;
  line-height: 38px;
}

.landing-page h2 {
  font-family: "HelveticaNeue", 'Open Sans', sans-serif;
  color: #3F4444;
  font-size: 20px;
}

.landing-page .navbar-default {
  border: 0;
}

.landing-page-accordion-ovarian .panel-default {
  border: 2px solid #004D74;
  border-radius: 100px;
  padding: 5px;
  text-align: center;
}

.landing-page-accordion-ovarian .az-panel-heading a {
  font-size: 24px;
  color: #004D74;
}

.landing-page-accordion-ovarian p {
  font-size: 17px;
  color: #000;
  text-align: left;
  padding: 15px;
}

.landing-page-accordion-ovarian .fa.pull-right {
  color: #004D74;
}

.landing-page-accordion-breast .panel-default {
  border: 2px solid #6810D4;
  border-radius: 100px;
  padding: 5px;
  text-align: center;
}

.landing-page-accordion-breast .az-panel-heading a {
  font-size: 24px;
  color: #6810D4;
}

.landing-page-accordion-breast p {
  font-size: 17px;
  color: #000;
  text-align: left;
  padding: 15px;
}

.landing-page-accordion-breast .fa.pull-right {
  color: #6810D4;
}

.landing-page-accordion-prostate .panel-default {
  border: 2px solid #801852;
  border-radius: 100px;
  padding: 5px;
  text-align: center;
}

.landing-page-accordion-prostate .az-panel-heading a {
  font-size: 24px;
  color: #801852;
}

.landing-page-accordion-prostate p {
  font-size: 17px;
  color: #000;
  text-align: left;
  padding: 15px;
}

.landing-page-accordion-prostate .fa.pull-right {
  color: #801852;
}

.landing-page a.underline {
  color: #000;
  text-decoration: underline !important;
}

.landing-page .sopc-text {
  font-size: 16px;
  color: #004D74;
  font-weight: 700;
}

.landing-page .reference-title {
  font-size: 18px;
  color: #004D74;
  font-weight: 700;
}

.landing-page ol li {
  font-size: 13px !important;
  color: #000;
  font-weight: 400;
}

.landing-page-cta-text {
  position: absolute;
  bottom: 41px;
  left: 30px;
  text-align: left;
}

.landing-page-cta-text h3 {
  font-size: 15px;
  color: #fff;
  margin: 0;
}

.landing-page-cta-text p {
  font-size: 10px;
  color: #fff;
  margin-top: -8px;
}

.summit-msd-az-logos {
  text-align: right;
  background: #fff;
  padding-bottom: 5px;
}

@media (min-width: 1920px) {
  .landing-page .container {
    width: 1200px;
  }
}

@media (max-width: 767px) {
  .summit-txt h2 {
    letter-spacing: 1px;
    font-size: 32px;
  }

  .landing-page-cta {
    width: auto;
    padding-bottom: 40px;
  }

  .landing-page .icon-bar {
    background-color: #fff;
  }

  .landing-page h1 {
    font-size: 26px;
    line-height: 32px;
    margin-top: 0;
  }

  .landing-page h2 {
    font-size: 18px;
    line-height: 22px;
  }

  .landing-page-accordion-ovarian .az-panel-heading a,
  .landing-page-accordion-breast .az-panel-heading a,
  .landing-page-accordion-prostate .az-panel-heading a {
    font-size: 19px;
  }

  .landing-page-accordion-ovarian .panel-default,
  .landing-page-accordion-breast .panel-default,
  .landing-page-accordion-prostate .panel-default {
    border-radius: 15px;
    padding: 0;
  }

  .landing-page-wrapper {
    padding-bottom: 0;
  }

  .landing-page .navbar-toggle {
    display: none;
  }

  .landing-page .pi-link {
    margin-top: 0;
  }

  .landing-page .navbar-header .new-image {
    top: -15px;
  }

  .landing-page-accordion-ovarian p,
  .landing-page-accordion-breast p,
  .landing-page-accordion-prostate p {
    font-size: 16px;
  }

  .landing-page-cta-text {
    bottom: 70px;
    left: 25px;
  }

  .landing-page-cta-text h3 {
    font-size: 13px;
  }

  .landing-page-cta-text p {
    font-size: 8.5px;
  }

  .landing-page-hcp-strapline p {
    font-size: 13px;
  }
}


/*landing page ends*/

/*Registration Pop-up start*/


.summit-banner {
  padding: 15px 20px 25px 20px;
  background: #004d74;
}

.close-btn {
  background: transparent;
  border: none;
}

.close-btn-sec {
  text-align: right;
}

.close-btn img {
  width: 55px;
}

.summit-txt h2 {
  font-size: clamp(26px, 38px, 3.5rem);
  color: #fff;
  font-family: 'HelveticaNeue-Medium';
  text-align: left;
  position: relative;
  border-left: 1px solid #d3d21f;
  padding-left: 40px;
  letter-spacing: 2px;
  font-weight: 100;
  padding-top: 13px;
  padding-bottom: 13px;
}

.summit-txt span {
  color: #b2d234;
}

.summit-b-content {
  display: flex;
}

.strip-grad {
  background: rgb(0, 77, 116);
  background: linear-gradient(90deg, rgba(211, 210, 31, 1) 0%, rgba(92, 146, 83, 1) 50%, rgba(0, 77, 116, 1) 100%);
  text-align: center;
  height: 3px;
}

.strip-grad h2 {
  font-size: clamp(21px, 28px, 31px);
  color: #fff;
  font-family: "HelveticaNeue", 'Open Sans', sans-serif;
  font-weight: 100;
  line-height: 1.2;
}

.m-0 {
  margin: 0 0;
}

.content-section {
  padding: 20px 32px 10px 32px;
  background: #fff;
}

.cont-sec-heading {
  font-size: 24px;
  font-weight: bolder;
  color: #004d74;
  line-height: 1.2;
  font-family: "HelveticaHeavy";
}

.cont-sec-subhead {
  font-size: 24px;
  font-weight: lighter;
  color: #004d74;
  line-height: 1.2 !important;
  font-family: "HelveticaNeue", 'Open Sans', sans-serif;
  font-weight: 100;
}

.cont-sec-subhead span {
  font-size: clamp(25px, 31px, 35px);
}

.para-con-sec {
  font-size: clamp(17px, 17px, 28px);
  font-style: italic;
  width: calc(100% - 19%);
  margin: auto;
  line-height: 1.2 !important;
  color: #004d74;
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
  font-weight: 100;
}

.mt-2 {
  margin-top: 15px;
}

.text-center {
  text-align: center;
}

.mb-2 {
  margin-bottom: 15px;
}

.border-text p {
  font-size: clamp(18px, 19px, 28px);
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
  line-height: 1.2 !important;
}

.border-text {
  border: 1px solid #000;
  padding: 10px;
  text-align: center;
}

.border-text a {
  color: #0563c1;
}

.dop p {
  font-size: 16px;
  color: #004d74;
  margin-bottom: 0;
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
  font-weight: 100;
  text-align: left;
  margin-top: 15px;
  margin-left: 0;
}

.cta-sec {
  background: rgb(211, 210, 31);
  background: linear-gradient(90deg, rgba(0, 77, 116, 1) 0%, rgba(92, 146, 83, 1) 50%, rgba(211, 210, 31, 1) 100%);
  padding: 16px 30px;
  color: #fff;
  text-align: center;
}

.cta-sec img {
  width: 60px;
  margin-left: 20px;
}

.cta-sec h3 {
  font-size: 30px;
  position: relative;
  font-family: 'HelveticaNeue-Medium';
  line-height: 1.2;
  color: #fff;
  font-weight: 100;
}

.cta-sec a {
  color: #fff;
  text-decoration: underline;
}

.border-text p a {
  word-break: break-word;
}

.cta-sec h3::before {
  content: '';
  background: url(/content/dam/open-digital/lynparza/en/oc-summit-22/mouse.svg) center;
  position: absolute;
  top: -10px;
  right: calc(100% - 86%);
  background-size: contain;
  width: 50px;
  height: 50px;
}

.summit-lynparza-logo {
  position: absolute;
  top: 0;
  right: 0;
}

@media screen and (max-width:1079px) {
  .summit-txt h2 {
    line-height: 1.2;
    letter-spacing: 0;
    margin-top: 15px;
  }

  #popup-template .cont-sec-subhead br {
    display: none;
  }

  .summit-logo img {
    width: 90%;
  }

  .summit-b-content {
    flex-wrap: wrap;
    justify-content: center;
  }

  .cta-sec h3::before {
    right: calc(100% - 88%);
  }
}

@media screen and (min-width:1080px) {
  .summit-logo img {
    width: 83%;
  }

  .cta-sec h3 {
    padding-right: calc(100% - 97%);
  }
}

#popup-template .modal-dialog {
  position: relative;
  width: auto;
}

@media screen and (min-width:992px) {
  #popup-template .modal-dialog {
    width: 92%;
    height: 100%;
  }
}

@media screen and (min-width:1440px) {
  #popup-template .modal-dialog {
    width: 1065px;
  }
}

#popup-template .modal-content {
  background: transparent;
  box-shadow: none;
  border: none;
}

#popup-template .modal-dialog button.close span {
  font-size: 37px;
  color: #fff;
  line-height: 0.6;
  font-weight: 100;
}

#popup-template .modal-dialog button.close {
  width: 36px;
  height: 36px;
  border-radius: 50%;
  border: 1px solid #801B52;
  margin-right: 30px;
  position: fixed;
  right: 0;
  top: 10px;
  background-color: #801B52;
}

#popup-template .modal-body {
  padding: 0;
}

.content-section a {
  text-decoration: underline !important;
}

.cta-sec a {
  text-decoration: underline !important;
}

.p-popup__header {
  background-color: #1e1e3a;
  color: #fff;
  padding: 20px 0;
  position: relative;
}

.p-popup__header-text h2, .p-popup__header-text p {
  color: #fff;
}

.p-popup__header h2 {
  margin: 0 0 24px;
}

.p-popup__header-text p {
  font-size: 22px;
}

.p-popup__header-img {
  position: absolute;
  position: absolute;
  top: 20px;
  right: 72px;
}

.p-popup__body {
  padding: 0 20px;
  background-image: url("/content/dam/open-digital/lynparza/en/webinar/bg-shape.svg");
  background-repeat: no-repeat;
  background-position: right -171px top -149px;
  background-size: 37%;
}

.p-popup__body h2 {
  font-size: 16px!important;
  font-weight: normal;
  color: #000;
  font-weight: bold;
  margin-top: 0!important;
}

.p-popup__body a {
  color: #000;
}

.p-popup__body p a:hover {
  color: #000 !important;
  cursor: pointer;
}

.p-popup__more-info-btn {
  font-size: 20px;
  background-color: #801B52;
  padding: 10px 50px 14px;
  color: #fff;
  display: inline-block;
  border-radius: 10px;
  margin-bottom: 20px;
  font-weight: bold!important;
}

a.p-popup__more-info-btn {
  color: #fff;
}

.p-popup__body a.p-popup__more-info-btn:hover {
  color: #fff;
}

.p-popup__more-info-btn span:nth-child(1) {
  text-decoration: underline;
}

.p-popup__more-info-btn span:nth-child(2) {
  margin-left: 18px;
}

.p-popup__more-info-btn:hover {
  background-color: #801B52 !important;
  color: #fff !important;
}

.p-popup__body p {
  font-size: 11px;
  margin-bottom: 12px;
}

.p-popup__para-normal--bold {
  font-weight: bold;
  max-width: 550px;
  margin: 0 auto;
  line-height: normal;
}

.p-popup__body p.p-popup__para-normal--large {
  font-size: 14px;
}

.p-popup__para-normal--large a {
  text-decoration: underline !important;
  font-weight: bold !important;
}

.p-popup__az-box {
  max-width: 832px;
  border: 1px solid #000;
  padding: 12px;
  margin: 0 auto;
  font-size: 12px !important;
  line-height: normal;
  margin-bottom: 16px;
}

.p-popup__footer-text p {
  font-size: 12px;
  text-align: left;
}

.p-popup__footer-images img {
  width: 220px;
}

@media screen and (max-width:576px) {
  .para-con-sec {
    width: 100%;
    font-size: 12px;
  }

  .cta-sec {
    padding: 10px 30px;
  }

  .strip-grad {
    padding: 12px 30px;
  }

  .summit-txt h2 {
    font-weight: normal;
    font-size: 18px;
    letter-spacing: 2px;
    margin-top: 10px;
    padding-top: 4px;
  }

  .border-text p {
    font-size: 12px;
  }

  .dop p {
    font-size: 12px;
    line-height: 1.2 !important;
  }

  .mt-2 {
    margin-top: 10px;
  }

  .summit-banner {
    padding: 11px 18px 14px 22px;
  }

  .summit-txt {
    margin-top: 10px;
  }

  .cta-sec h3,
  .strip-grad h2 {
    font-size: 14px !important;
  }

  .cont-sec-heading {
    font-size: 14px !important;
  }

  .cta-sec h3::before {
    right: calc(100% - 102%) !important;
    width: 40px;
    height: 40px;
  }

  .cont-sec-subhead {
    font-size: 12px !important;
    margin-top: 6px;
  }

  .summit-logo img {
    width: 50%;
    margin-top: 80px;
  }

  #popup-template .modal-dialog button.close span {
    font-size: 45px;
  }

  #popup-template .modal-dialog button.close {
    width: 35px;
    height: 35px;
    top: 14px;
  }

  p.extra-link-txt {
    font-size: 12px !important;
    line-height: 1.2 !important;
  }

  .jbn-cl p {
    font-size: 12px !important;
    line-height: 1.2 !important;
  }

  .content-section {
    padding: 10px 15px 10px 15px;
  }

  .jbn-cl {
    margin-left: auto;
  }
}

@media screen and (max-width:472px) and (min-width:375px) {
  .cta-sec h3::before {
    right: calc(100% - 97%);
  }
}

@media screen and (max-width:992px) and (min-width:767px) {
  .cta-sec h3::before {
    right: calc(100% - 94%);
  }
}

@media screen and (min-width:768px) {

  .summit-logo,
  .summit-txt {
    width: 49%;
  }

  .summit-logo img {
    width: 85%;
  }

  .summit-logo {
    text-align: left;
  }

  .summit-logo {
    width: 31%;
  }

  .jbn-cl {
    width: 20%;
  }

  .summit-b-content {
    align-items: end;
  }
}

.jbn-cl {
  align-items: end;
  display: flex;
  text-align: right;
  justify-content: end;
}

.jbn-cl p {
  color: #fff;
  margin-bottom: 0;
  font-size: 17px;
}

p.extra-link-txt a {
  color: #0563c1;
}

p.extra-link-txt {
  font-size: 17px;
  color: #004d74;
  margin-bottom: 0;
  font-family: "HelveticaNeue", 'Open Sans', sans-serif !important;
  font-weight: 100;
  text-align: center;
  margin-top: 10px;
}

@media screen and (max-width:767px) {

  .summit-logo,
  .summit-txt {
    width: 100%;
    flex-wrap: wrap;
  }

  .cta-sec h3::before {
    right: calc(100% - 97%);
  }

  .cont-sec-heading {
    font-size: 28px;
  }

  .cont-sec-subhead,
  .strip-grad h2 {
    font-size: 25px;
  }
}

#popup-template .modal-content {
  padding: 0;
  height: 100%;
}

#popup-template .modal-header {
  padding: 0;
}

#popup-template .modal-dialog {
  margin: 20px auto;
  height: 100%;
  padding: 0 10px;
}

.summit-logo {
  width: 290px;
  margin-top: 0;
}

#popup-template .modal-content {
  background: transparent;
  box-shadow: none;
  border: none;
}

#popup-template .modal-dialog .modal-body {
  overflow-y: scroll;
  background-color: #fff;
  border-radius: 14px;
  font-family: "AlbertSans";
  min-height: fit-content;
}

/*#popup-template .modal-dialog .modal-body h2, #popup-template .modal-dialog .modal-body p {*/
/*  font-family: "AlbertSans"!important;*/
/*}*/

@media screen and (min-width:940px) {
  .dop {
    display: grid;
    grid-template-columns: 18% 82%;
  }

  .dop p.extra-link-txt {
    text-align: right;
  }
}

@media screen and (max-width:939px) {
  .dop {
    grid-template-columns: auto;
    text-align: center;
  }

  .dop p.extra-link-txt {
    margin-top: 5px;
    text-align: center !important;
  }
}

.dop p.extra-link-txt a {
  color: #0563c1;
}

#popup-template {
  padding-left: 0 !important;
}


/*Registration Pop-up end*/


/************* Navigation Jan 25 update************/
.landing-page .primary-navigation .nav>li:first-child {
  display: none;
}

/*********** Navigation Jan 25 update *************/

.study-19 .hcp-strapline, .solo-2 .hcp-strapline, .paola-1 .hcp-strapline {
  top: 66px;
}

.dosing .title-bar, .hrd-testing .hrd-cols {
  padding-top: 53px;
}

@media (min-width:768px) {
  .study-19 .hcp-strapline, .solo-2 .hcp-strapline, .paola-1 .hcp-strapline {
    top: 71px;
  }

  .dosing .title-bar, .hrd-testing .hrd-cols {
    padding-top: 78px;
  }
}

/*Webinar Pop-up*/
.personal-popup #popup-template .modal-dialog button.close {
  background-color: #801B52;
  border-color: #801b52;
  color: #fff;
}

.personal-popup #popup-template .modal-dialog button.close span {
  color: #fff;
}

.p-popup__logo {
  width: 100px;
}

.p-popup__card {
  width: 146px;
  display: flex;
  flex-direction: column;
  justify-content: center;
  align-items: center;
}

.p-popup__card img {
  width: 90px;
}

@media (min-width:1024px) {
  #popup-template.modal {
    overflow: hidden;
  }

  #popup-template .modal-dialog .modal-body {
    overflow-y: hidden;
  }

  p.bottom-jbn {
    padding: 0 42px;
  }
}

@media (min-width:1200px) {
  p.bottom-jbn {
    padding: 0 15px;
    max-width: 1178px;
  }
}

/*popup august 25*/


.oc-popup-aug25 {
    
    button.close{
    background-color: #B2D234 !important;
    border: 1px solid #B2D234 !important;
}
button.close span{
    color:#004D74 !important;
}
  

.header {
  background-color: #004D74;
  color: #fff;
  padding: 8px 0 16px;
  display: flex;
  flex-direction: column;
  align-items: center;
  
}
.header .wrapper h2 {
font-family: "Inter-bold";
  color: #fff;
  margin: 0;
  font-size: 24px;}

.pill-sm {
  background-color: #AAE2FF;
  border-radius: 9px;
  color: #004D74;
  font-family: "Inter-bold", sans-serif !important;
  font-size: 10px;
  font-style: normal;
  font-weight: 900;
  line-height: 24px;
  letter-spacing: -0.457px;
  margin-bottom: 6px;
}

.header .wrapper p {
  width: 170px;
  margin: 0 auto;
  color: #fff;
  font-size: 12px;
  line-height: 14px !important;
  font-family: "Inter-extra-light", sans-serif !important;
}
        

.lime-bg {
  background-color: #F0F6D6;
  padding: 16px 10px 24px;
};

.badges-container {
  display: flex;
  justify-content: space-between;
  gap: 16px;
}

.badges-container .badge-text {
  color: #004D74;
  font-size: 10px;
  line-height: 13px;
  margin-top: 16px;
  font-family: "Inter-bold"
}

.p-lg {
  font-size: 12px;
  color: #004D74;
  font-weight: 600;
  font-family: "Inter-semibold", sans-serif !important;
}

.text-content {
  padding: 14px 14px 8px;
  text-align: left;
  color: #004D74;
  font-size: 10px;
}
.text-content b{
    font-family: "Inter-bold" !important;
}

.text-content b, .text-content p {
  color: #004D74;
  font-size: 10px;
  line-height: 1 !important;
}
.text-content p{
      font-family: "Inter-regular" !important;
}

.text-content p a {
  text-decoration: underline;
  color: #004D74;
  font-weight: bold;
}

.pill-xl {
  background: #B2D234;
  border-radius: 43px;
  padding: 9px 30px;
  text-align: center;
  margin-bottom: 12px;
}

.pill-xl h3 {
  color: #004D74;
  font-family: "Inter-bold";
  font-size: 12px;
  font-style: normal;
  font-weight: 700;
  line-height: 1;
 /* 344.828% */
  letter-spacing: -0.057px;
  margin: 0;
}

.pill-xl h3 a {
  text-decoration: underline !important;
  color: #004870;
  margin: 0;
}

.pill-xl a{
    font-weight:bold;
}

.pill-xl p {
  color: #004870;
  font-size: 8px;
  font-weight: 400;
  line-height: 1 !important;
  margin-bottom: 0;
  font-family: "Inter-regular", sans-serif !important;
}

.adverse-box {
  color: #004D74;
  font-size: 10px;
  font-family: "Inter-regular";
}

.adverse-box a {
  color: inherit;
  font-weight: bold;
  font-family: "Inter-semibold";
}
.abbr{
    font-family: "Inter-regular" !important;
}

.text-content ol {
  padding-left: 0;
  list-style-position: inside;
  margin-bottom: 0;
  margin-top:4px;
}

.text-content ol li {
  color: #004870;
  font-size: 9px;
  line-height: 11px !important;
  font-family: "Inter-regular" !important;
}

.text-content ol li a {
  color: #004870;
}

.adverse-box {
  padding: 8px;
  margin: 0;
  border: 1px solid #004d74;
  margin-bottom: 9px;
  line-height: 11px;
}

.footer {
  display: flex;
  font-size: 9px;
  padding: 18px 11px;
  background-color: #004D74;
  align-items: center;
  justify-content: space-between;
  margin-top:0;
}

.footer p {
  font-size: 9px !important;
  margin-bottom: 0;
  color: #fff;
  font-family: "Inter-light" !important;
}

.footer img {
  margin-bottom: 5px;
}

@media (min-width:768px){
    .modal-dialog{
        max-width:900px;
    }
    .header{
            padding: 20px 38px 18px;
    display: grid;
    grid-template-columns: 100px auto;
    }
    .header .wrapper h2{
        font-size: 44px;
    }
    .pill-sm{
            padding: 5px 22px;
    font-size: 12px;
    font-weight: bold;
    border-radius: 12px;
    }
    .heading{
            display: flex;
    align-items: center;
    justify-content: center;
    gap: 14px;
    margin-bottom:12px;
    }
    .header .wrapper p{
            width: 512px;
    font-size: 22px;
    line-height: 24px !important;
    }
    .lime-bg{
        padding: 9px 58px 20px;
    }
    .p-lg{
    font-size: 17px;
    }
    
    .badges-container .badge-text{
        font-weight: 600;
        font-size: 15px;
    }
    .pill-xl h3 {
  font-size: 20px;
  margin-bottom:8px;
}

.pill-xl a{
    font-weight:bold;
}

.pill-xl p {
  font-size: 13px;
  
}
.text-content {
  padding: 15px 38px 9px;

}
.text-content p:nth-child(4), .text-content p:nth-child(5){
    font-size:12px;
}
.text-content b{
    font-size: 12px;
}
.adverse-box {
  font-size: 9px;
  padding: 8px 12px;
  margin-top:17px;
  margin-bottom: 10px;
}
.abbr{
    margin-bottom:0;

}
.footer {
  padding: 16px 28px;
}
.footer p {
  font-size: 10px !important;
}
    }}